Sentence examples for a key interaction from inspiring English sources
B) The space available for a hydrogen bond-accepting atom forming a key interaction with Gly 253 (red-dotted sphere).
This feature reflects a key interaction between potent agonist and PPARγ receptors, which shows concurrence with the inference of the X-ray crystallography depicted in the next section.
Other shared but non-residue specific interactions include the anchoring hydrogen bonds at the hinge, and a key interaction with a main chain carbonyl group.
The possible formation of a three-centred hydrogen bond (HB) at the HB donor site H2, as a key interaction for high receptor binding affinity, was assessed by the calculation and comparison of the molecular electrostatic potentials of a series of selected ligands.
Three-dimensional structures of the glucose importagog SC4 bound to activated α2β2γ1 and α2β1γ1 complexes reveal binding determinants, in particular a key interaction between the SC4 imidazopyridine 4′-nitrogen and β2-Asp111 β2-Asp111ovide a design paradigm for β2-AMPK therapeutics.
These reports support our finding that Trp222 in PKA and Trp427 in Pak2 is a key interaction site with Thr197 PKA) in PKA and Thr402 in Pak2.
The pinch/parvin interaction is shut down in cultured podocytes (see Figure 5), making it a candidate key interaction reflecting podocyte dedifferentiation in cell culture.
Household energy consumption is a process that involves key interaction between the environment and the economy, as demonstrated in Fig. 1.
The crystal structure presented here demonstrates that it does not, and shows that the binding is well described by a classic "lock and key" interaction.
Using mutagenesis experiments, we demonstrate that the mechanical stabilization effect is due to only a few key interactions of the protein with its ligand.
The reason for the latter is that very small ligands (five atoms or less) only make a few key interactions with the protein and can bind non-specifically.
