Sentence examples for a key damage from inspiring English sources

The onset of buckling of longitudinal bars in reinforced concrete columns is a key damage state (Fig. 4) because unlike less severe levels of flexural damage, bar buckling requires extensive repairs (Lehman et al. 2001), significantly reduces the structure's functionality (Eberhard 2000), and has clear implications for structural safety.

Processing and secretion of inactive pro-IL-1β requires a secondary stimulus, the best-studied being ATP, a key damage-associated molecular pattern (DAMP) (Lister et al., 2007).

If you fail a key assignment, damage a client relationship, mismanage an interaction with a supplier, you can't make it up or ask for extra credit.

Here, we show that ETS family members, such as ERG and ETV1, directly repress the expression of the checkpoint kinase 1 (CHK1), a key DNA damage response cell-cycle regulator essential for the maintenance of genome integrity.

On the other hand, because agriculture is a key sector, damage to this sector has potential negative impacts on other economic sectors, which can be further understood through backward and forward linkage multipliers.

Translesion DNA synthesis is a key DNA damage tolerance mechanism that enables cells to overcome replication blocks caused by bulky DNA lesions unsurpassable for replicative DNA polymerases.

For example, a tumour suppressor gene, p53, is a key DNA damage mediator that plays a dual role following exposure to cytotoxic treatment (Ferrera et al, 1999); it is involved in damage-induced apoptosis, but also plays a role in cell cycle arrest and DNA repair, cellular processes that can affect the sensitivity to chemotherapeutic drug.

In 2013, while he was still editor, Mr. Hayes retracted a key study damaging to Monsanto that found that Roundup, and genetically modified corn, could cause cancer and early death in rats.

In spite being at the end of this list, humidity is often seem as a key driver for damage to indoor materials in contrast to outdoor damage, where it is water as a liquid is so important.

Cognitive impairment is a known consequence of cerebral small-vessel disease and recent neuroimaging studies suggest that occult cerebrovascular damage plays a key role in brain damage and dysfunction in COPD [ 55, 56].

No creep cavitation is visible by microscopic observations, while the environment is found to play a key role in damage accumulation and interaction.