Activating mutations in the Kras oncogene have been observed in PanIN lesions, suggesting that deregulation of Ras signaling is a key component during the transformation of epithelial cells [29], [30].
Since migration of monocytes across blood vessel lining endothelial monolayers is a key component during early stage of atherosclerosis, such an outcome would indicate that SIRPα overexpression in monocytes or macrophages has an anti-atherogenic effect and that SIRPα is a potential target in therapeutical implications.
Communication with incoming travelers was a key component of border activity during the SARS and influenza A(H1N1 pdm09 virus pandemics and during other disease outbreaks (8, 35, 36 ).
And so it came to pass, a record made by playing other peoples' records – Grandmaster Flash had broken the fourth wall of the recording industry, and by the end of the decade his influence would be heard everywhere, as hip-hop and turntablism became a key component of popular culture during the late 20th century.
Phillips presses this point further by arguing that the management of natural resources became a key component of federal planning during this period.
Heritable modification of chromatin or DNA leading to fixation of gene expression programs is a key component in demarcating potential during development.
In order to ensure that the precise amount of myelin is formed at the right developmental stage and in the correct place, a key component of oligodendrocyte behaviour during myelin formation must be the integration of multiple extrinsic signals at the axon surface along with intrinsic programmes, such as autonomous developmental timers of differentiation.
In another study, phosphorylated histone H3, a key component involved in chromosome compaction during cell division, was found increased in the cytoplasm of hippocampal neurons in AD, rather than within the nucleus as in actively dividing cells [ 38].
Leslie and Storton, in another research, also showed that the unrestricted presence of a birth companion of the women's choice, including husbands, partners, children, family members, and friends, was a key component regarding women's satisfaction during their birth experience [ 36].
Thus, the remote handling (RH) maintenance system should be a key component, which must be detailedly designed during the concept design processing of CFETR, for the operation of reactor.
The bi-phasic production of apoplastic ROS, the so-called oxidative burst, is a hallmark of successful recognition of plant pathogens and a key component of the plant defense response during an incompatible interaction.
