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Slaughterhouses have also been implicated as a key checkpoint for the detection of pathogens such as Campylobacter [ 22] and Salmonella [ 23, 24], and in case of poor biosecurity could also result in the spread of pathogens between premises where dirty equipment is reused.
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The protein is a potent inhibitor of cyclin-dependent kinases and is known to be a key checkpoint protein for the transition of keratinocyte growth/differentiation [20].
The groups secured artillery and ammunition, and gained control of a key checkpoint in the town of Tabqa (unknown casualties).
Mad2 is a key checkpoint component that undergoes conformational activation, catalyzed by a Mad1-Mad2 tenrichedenriched at unattached kinetochores [ 5].
The progression from G1 to S is a key checkpoint in protecting the cell from abnormal replication.
Thus, PTEN is a key checkpoint in the Akt signaling pathway and its dysfunction triggers RTKs-dependent oncogenesis.
A better understanding of the vascular transport of CTCs can reveal key checkpoints for the intervention and treatment of metastasis.
However, we found that Set2 levels were still decreased in a number of key checkpoint mutants tested (Supplementary Fig. 4e).
The balance between these key checkpoint proteins is critical for progression through each step of the cell cycle to occur.
Cdk8 module RNAPII antagonism for Mediator binding represents a key regulatory checkpoint.
Gene expression analysis was carried out with a customized 770-gene expression panel combining markers for 24 different immune cell types and 30 common cancer antigens, including key checkpoint blockade genes analysed with the Ncounter system.
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