The phrase "a interacting" is not correct in English.
Did you mean "an interacting"? If this is the case, you can use it when referring to an interaction that is ongoing or happening at the moment.
Example: "We had an engaging discussion, and it was an interacting experience that brought us closer together."
Alternatives: "an engaging" or "a dynamic".
However, this is not true for probes dual labelled at the 5′- and 3′-positions by a D and an A interacting by FRET, in that the D-to-A distance cannot remarkably overcome the Förster radius.
Docking of this compound with the BRAF structure in the active conformation (pdb code 2FB8) showed the expected orientation of the compound, similar to SB590885, with the pyridyl ring A interacting with the hinge and the 4- 3-pyrazolyl phenyl ring B occupying the BPII pocket (Fig. 2).
On the other hand, HSP90 can negatively affect apoptosis by (a) interacting with Apaf-1 and consequently blocking the apoptosome formation [ 100 ]; (b) interacting with Akt that, in turn, leads to inactivation of proapoptotic Bad protein and caspase-9, and to activation of NF κ B apoptosis inhibition mechanism [ 101 ]; (c) inhibiting the action of calpains.
Not all Aurora A interacting factors activate the kinase.
Six tryptic polypeptides were completely matched to the sequence of mouse L-FILIP (filamin A interacting protein 1).
For example, BAG3 was identified as a interacting partner of MMP-2, knockdown of BAG3 reduced MMP-2 expression, and invasiveness in MMP-2-positive ES2 ovarian cancer cells.
In the present study, our in silico analysis showed that bacosides (A3, A) interact with TPH.
Upon activation, Rho A interacts with and activates the Rho A-dependent kinase (ROCK).
Cells expressing mutant AR that lack a filamin-A interacting domain fail migrate in response to androgen stimulation [ 79].
Third, Aurora-A interacts with the CUL3-KLHL18 ligase through direct interaction with KLHL18.
It generates an interacting patch and a non-interacting patch for each training protein.
