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The advantage of the adaptive design over a initial study assessing concordance and a subsequent study assessing difference in treatment effect is that the first-stage patients can be included when the original biomarker is used, providing a higher power.
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It is now much clearer to me that this work was a supplement to an initial study performed to understand commercialization on campus.
The trials are in four phases: Phase I, an initial study in a small group, establishes whether a treatment is safe and at what dosage.
Instart Logic can analyze how people use a site, and even before the sale, show speed improvements based on an initial study of a particular website.
The report is a follow-up to an initial study of the Angola "conflict diamonds" trade this year commissioned by the Council under the direction of Canada.
"This is an initial study with a very small sample that shows us that the technology may be of use in C.T.E.
As an initial study using a novel approach, we used relatively unrestricted conditions to set up a rough HypoGen model.
In conclusion, this is an initial study on a limited number of patients showing some promising data.
Again there is a certain irony when an initial study that is almost universally dismissed as methodologically flawed is used to set the standard for future studies.
The watchdog said a review was needed after an initial study found "the banking industry is not straightforward and that a more detailed examination is needed".
The delivery under a dynamic condition would be an initial study of in vivo localized delivery of growth factors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com