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Although earlier studies showed that neither immunosuppressive drug had an effect on invasive candidiasis, recent studies have shown that cyclosporin A impairs innate immunity (Greenblatt et al., 2010).
Mutant allele A impairs interactions between IRF5 mRNA and miR-181a/664 while enhancing binding-site of IRF5 and miR-543/4477a/4729.
33, 46, 48 In the case of LQT11, a mutation within AKAP9, which encodes an A kinase-anchoring protein responsible for facilitating phosphorylation of KCNQ1 by protein kinase A, impairs IKs augmentation, leading to a clinical phenotype similar to that for LQT1 and LQT5.
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Here, we demonstrate that downregulation of JAM-A impairs the ability of MDCK II cells to form cysts in a three-dimensional matrix indicating the requirement of JAM-A for the development of apico-basal polarity.
For example, the strong association between integrin and filamin-A impairs migration [ 105], and the competition binding by talin to replace filamin-A can resume signaling and movement, which altogether underscores the importance of a balance of multiple interactions during migration [ 66, 67, 105].
A well-performing, an impaired, and an intermediate family cluster emerged from the analysis.
Nevertheless, patients with higher S100A6 serum concentrations showed a trend towards an impaired prognosis compared to patients with lower levels.
Greece entered the crisis as a dysfunctional state with an impaired economy.
For instance, a typo could cause an impaired case when not using pre-processing assertion rules.
Migraine seems to be a clinical marker of an impaired microvascular autoregulation [ 33].
Williams syndrome (WS) is a neurodevelopmental disorder associated with an impaired capacity for visuospatial representation.
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