Sentence examples for a human framework from inspiring English sources

A chimeric version of anti-CD40L Fab was generated by transferring mouse variable regions into a human framework.

So, although in its framing, editing and analogizing it does impose a human framework on the unknowable intelligences of its subjects, we are thankful (on balance) for the seven-part "North America," premiering Sunday on Discovery Channel.

Here we describe the in vitro and in vivo activity of synthetic SUDV-specific antibodies containing a human framework.

Here we describe monoclonal antibodies containing a human framework that potently inhibit infection by SUDV and protect mice from lethal challenge.

Here we describe the isolation and characterization of protective SUDV-specific mAbs with a human framework using a synthetic antibody approach.

The synthetic phage antibody library described here utilizes a single human framework with a template containing human consensus complementarity-determining regions (CDRs).

The libraries were generated using a single human framework with a template containing human consensus complementarity-determining regions (CDRs) [ 62] and the antibodies that cross-react with both human and murine NRP were generated.

Phage-displayed synthetic antibody libraries were built on a single human framework by introducing synthetic diversity at solvent-exposed positions within the heavy chain complementarity-determining regions (CDRs).

Simple grafting of six CDRs of the chicken antibody into a homologous human framework (FR) template resulted in the complete loss of pT231-peptide binding.

We describe complete methods for the design, construction, and application of simplified synthetic antibody libraries built on a single human framework with diversity restricted to four complementarity-determining regions and two amino acids (tyrosine and serine).

Humanization of a potent neutralizing mouse anti-human IL-13 antibody (m836) using a method called human framework adaptation (HFA) is reported.