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The phrase "a huge problem in" is correct and usable in written English.
It can be used to describe a significant issue or challenge within a specific context or area.
Example: "Climate change is a huge problem in our society that requires immediate attention."
Alternatives: "a major issue in" or "a significant challenge in".
Exact(56)
"We have a huge problem in Florence," Ms. Prebys said.
Blur is a huge problem in those situations.
"It's exposed a huge problem in our intelligence gathering.
"Homelessness is a huge problem in Manchester," Hall said.
Food insecurity is a huge problem in Malawi.
On the contrary, excessive executive compensation is a huge problem in corporate America.
Not having health insurance is a huge problem in Mississippi, but it isn't the only one.
And infant mortality — especially neo-natal deaths — remain a huge problem in many countries.
We have a huge problem in advertising – one that few have been keen to address.
"Bride price is a huge problem in rural communities like Katine," says Mifumi's Okoth.
Everyone knows that heavy workloads are a huge problem in teaching.
More suggestions(16)
a great problem in
a huge dilemma in
a large problem in
a huge challenge in
a sizeable problem in
a remarkable problem in
a massive problem in
a monumental problem in
a tremendous problem in
a vast problem in
a huge increase in
a huge stigma in
a huge difference in
a universal problem in
a huge advantage in
a huge following in
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com