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The phrase "a huge negative" is correct and usable in written English.
It can be used to describe a significant disadvantage or drawback in a situation or context.
Example: "The lack of funding for the project is a huge negative that we need to address before moving forward."
Alternatives: "a major drawback" or "a significant downside."
Exact(60)
"It was a huge negative campaign," he told the BBC.
Negative rates haven't worked, in fact they have been a huge negative".
On the other, this will make a huge negative impact on future emissions coming from Brazil".
The firm would be sending a huge negative signal about companies it didn't reinvest in — hardly an entrepreneur-friendly stance.
Woodhead told the TES that teaching unions were a "huge negative influence on the public perception of the profession".
His answer was always we have to beat Jeb Bush, because he knows in the black community Jeb Bush is a huge negative.
The bathroom scale is a pervasive computing device that decreases admissions, but if congestive heart failure is my biggest profit center, that could have a huge negative impact".
"Getting rid of the tracking stock, which was really just a Wall Street invention, removes a huge negative," said Jeffrey Hines of Deutsche Bank.
This inflicted a huge negative "pecuniary externality" on Fannie and Freddie, driving up house prices in the normally sound mortgage markets they serve.
I am part of that community; we agree that human greenhouse gas emissions are having a huge, negative effect on global climate.
"These cuts would have a huge, negative impact on the most vulnerable Americans who count on these programs to make ends meet," Mr. Baucus said.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com