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Among them, 11 ligands induced a huge modification of the uranyl biodistribution by deviating the metal from kidney and bones to liver.
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A huge change.
As a matter of fact, this design is tailored to the Wildforce board and it cannot be reused for another board without huge modifications.
The presence of a huge number of modifications, however, indicates that this method is highly unstable and still awaits improvements.
In most cases it is easy to determine what is wrong with a patient, but behavior modification is a huge challenge.
Polycarbonate has exhibited a huge sensitivity to such geometric scale modifications while no modification has been observed for PMMA.
A better understanding of the covalent modifications of oligomers could have a huge impact on the development of therapeutics for neurodegenerative diseases.
This modification of inclusion criteria led to a huge increase of up-regulated genes.
In addition to chromosomal translocations, modifications to histone could also place a huge impact on the 3 D structure of chromatin and has been widely implicated in cancer.
The MDOCA algorithm is a modification of a standard variable step gradient algorithm that yields a huge saving in computational cost.
The existence of the language in the bracket "(not including a modification to the structure of the biological product)"--actually does create a huge evergreening loophole.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com