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The phrase "a huge effect on" is correct and usable in written English.
It can be used when discussing the impact or influence that something has on another thing or situation.
Example: "The new policy had a huge effect on employee morale and productivity."
Alternatives: "a significant impact on" or "a major influence on".
Exact(60)
It had a huge effect on me".
Loneliness has a huge effect on eating.
The event had a huge effect on shifting public mood.
This could have a huge effect on votes.
"It has a huge effect on global climate".
"He still has a huge effect on our play".
They also had a huge effect on my standup.
That distinction has a huge effect on how we cook.
"That had a huge effect on me," he said.
It hasn't had a huge effect on us.
But it has had a huge effect on them.
More suggestions(20)
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a huge implication on
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a significant effect on
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com