The phrase "a highly significant extent" is correct and usable in written English.
It can be used to emphasize the importance or magnitude of something in a particular context.
Example: "The research findings indicate that the new policy has improved employee satisfaction to a highly significant extent."
Alternatives: "a considerable degree" or "a substantial level".
Furthermore, there was a highly significant positive correlation between the extent of TFP-induced loss in LysoTracker retention and the magnitude of cytotoxicity.
Our prostate tissue array investigations show that there was a highly significant (p<0.0001) increase in both the total area (extent) and average size of the labelled particles (intensity) and area fraction (Fig 1E, F and G and Table S2).
There was a mononuclear, T cell-dominated infiltration consisting of CD4+ and to a lesser extent CD8+ T cells and a highly significant increase in IFN-γ, both at the level of mRNA and protein expression.
It was shown that a highly significant negative correlation between parenchymal mean SWV and RFA extent.
For fat intercept, a highly significant SNP was found on BTA5, which also affected slope to a lesser extent.
As shown in Table 7, these comparisons revealed a highly significant risk associated with the S2/S3P, S3P and S1/S3D groups and, to a lesser extent, S1 and S3D as described in previous studies [ 21, 40].
Also, the preoperative C1-INH concentration had a highly significant effect on time to recurrence of cancer (P = 0.0007), adjusting for age and disease extent.
We found a highly significant copositioning of these stabilizing elements with the genes coding for secreted proteins, and, to a lesser extent, with genes coding for outer membrane proteins (p < 0.0001, Wilcoxon test).
Prin1 showed a highly significant correlation to the genomic GC content (R = 0.9394, p < 0.0001), indicating that, to a large extent, genomic GC content determined amino acid usage.
