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At the same time, the high diversity of mitochondrial proteins, with different composition and conformations, makes the selection of a universal standard for proteins a highly problematic task.
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"What we see clearly as a glorious capstone to his career," Ellis writes, seemed to Washington "more like a highly problematic sequel".
This is a highly problematic passage.
Burkholderia cenocepacia J2315 is representative of a highly problematic group of cystic fibrosis (CF) pathogens.
In contrast to older views, the harmony and complementarity of interests is a problematic task, an aspect of rational self-shaping, rather than a preconceived given.
Designating a species status can be a problematic task and the underlying concepts are subject of ongoing discussions (e.g., Templeton 1998; Avise 2000; Schroth et al. 2002).
Designating a species status can be a problematic task and the underlying concepts are subject of ongoing discussions [e.g. [ 23].
Seeking an analytical solution to the developed equations, particularly in their general form, is a very problematic task.
Not surprisingly, even in psycholinguistics tracing a neat functional separation between word processing and general-purpose cognition has proven a problematic task.
Dr. Tuman said the policy set up the newspapers for a problematic task: verifying those mountains of documents.
Selecting the specific surgical procedure to use is a problematic task.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com