The phrase "a highly efficacious" is correct and usable in written English.
It can be used to describe something that is very effective or successful in producing a desired result.
Example: "The new treatment has proven to be a highly efficacious solution for patients suffering from chronic pain."
Alternatives: "very effective" or "extremely successful".
Further optimization focusing on maximizing in vivo efficacy and minimizing CYP3A4 time-dependent inhibition resulted in a highly efficacious compound (6s) in tumor xenograft model for further preclinical development.
Evidence supports the feasibility of developing a highly efficacious malaria vaccine.
A reasonable sample size was estimated to be 40 50 patients per group, if a highly efficacious drug was used.
Ureteroscopy has been shown to be a highly efficacious and safe modality for the treatment of pediatric urolithiasis.
Over one-third (34.6%) reported intentions to increase post-vaccination risk behaviors in response to a highly efficacious HIV vaccine.
Targeting PD-L1/PD-1 signaling has been shown to be a highly efficacious cancer immunotherapy (Brahmer et al., 2012; Topalian et al., 2012).
Gel efficacy is very important, with a very highly efficacious gel potentially reducing HIV incidence by 19.0%, while a gel with poor efficacy provides little population protection.
Hence, critical formulation variables, i.e. the lipidoid content and siRNA:lipidoid ratio, were initially identified, followed by a systematic quality-by-design approach to define the optimal operating space (OOS), eventually resulting in the identification of a robust, highly efficacious and safe formulation.
We have established that a potential highly efficacious combination strategy of this kind, could be metformin and the copper-bis(thiosemicarbazones), Cu-GTSM or Cu-ATSM.
ABT-207 and in particular the h5F9-AM8 which acts as a specific and highly efficacious antibody with a relatively long half-life seem suitable for medical indications in which hepcidin upregulation plays a role.
These results provide evidence that the novel PAMAM-bioactive complex is a simple yet highly efficacious system, with a great capability to cross the BBB and thus delivery CNS targeted drug successfully [ 98].
