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This is a highly connected network with an average of 7.74 connections per gene set.
There's no way to verify this without neural imaging, but we would expect Krantz's brain to have a highly connected network of neural pathways in the right hemisphere.
For example, when the researchers analyzed the molecular pathways in which the genes participate, they discovered that most of the pathways can be placed in a highly connected network of genes that are already known to affect cancer.
We report a highly connected network underlying de novo variants discovered in an autism trio exome-sequencing effort, and we design, test and implement a novel statistical framework ("DAPPLE/SEQ") to analyze rare inherited variants in the context of PPIs in a way that significantly boosts power to detect association.
In recent years the results of post-genomic and network biology showed that proteins rarely act in isolated systems but rather as a part of a highly connected network [1].
Diversity is diminished by increased connectivity, but has a more complex relationship with network structure, for example, a highly connected network may exhibit low overall diversity but maintain high diversity in a small number of low degree nodes in the periphery of the network.
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The interaction information we collected contributed to assemble an intricate and highly connected network consisting of 1555 nodes and 2496 edges (Fig. 4A).
A more dense, or more highly connected, network may be useful for sharing information and resources and cooperation, whereas a more sparsely connected network may provide greater access to diverse contacts and novel resources [ 10, 18].
The most highly connected network identified represented a cluster of genes involved in glutamatergic synaptic transmission.
A substantial reduction in infection and mortality is observed when both the elderly/retired and children are cut off from the highly connected network of such cities.
In addition, visualization and navigation of links in the highly connected network poses its own set of computational challenges.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com