Sentence examples for a highly complex regulation from inspiring English sources

It has been reported that autophagy may delay the DNA damage response and apoptotic death in breast cancer cells [ 35] and this duality indicates a highly complex regulation of cell fate post therapy.

These results are consistent with demonstration of expression of TG1, TG2, TG3, and TG5 in the brain (Kim et al. 1999; Bailey and Johnson 2004; Bailey et al. 2004) and together with cell biological studies points to a highly complex regulation of TG genes in the CNS.

Our results also raise the interesting speculation that while in plants the high GC content of the gene may be a major obstacle for translation while in mammalian cells, normally growing at a much higher ambient temperature (typically 10°C to 20°C higher) the region provides for yet another potential checkpoint for the highly complex regulation of ACHE gene expression in mammals [ 60].

The overriding impression was that of a highly complex research regulation system, partly varying between different types of research and involving a range of actors.

It is obvious that the regulation of blood flow and oxygen transport is a highly complex and regulated system that integrates cellular needs with vascular regulation mechanisms.

Distinct expression patterns within each gene family in berries and a range of other grapevine tissues suggest spatial and temporal specification and hence a highly complex system for the regulation of cytokinin concentrations and responses.

The pre- and post-veraison-specific expression of different members from each of five gene families suggests a highly complex and finely-tuned regulation of cytokinin concentrations and response to different cytokinin species at particular stages of fruit development.

Body weight regulation is a highly complex process that involves the GI tract and adipose tissue in addition to the hypothalamus and pancreas discussed above [37].

It is clear that HIF-1 α regulation pathway is a highly complex network involving several signaling cascades and overlapping mechanisms, each of which could serve as a promising target or step to intervene selectively.

A Cac_3319 mutant showed significantly reduced sporulation activity as well as increased butanol production [ 45, 46], showing solvent production regulation to be a highly complex and relatively poorly understood process.

Finally, we show how TF concentration can modulate many aspects of the promoter activity in a highly complex and flexible manner, suggesting the transcriptional regulation as a central piece for the cell to control and take advantage of stochasticity.