At the level of the whole organism, Alhonen et al. [ 49] could not observe a higher level of spontaneous tumor incidence in transgenic mice overexpressing human ODC under its own promoter.
Although pandemics are typically characterized by their occurrence over a short span of time, today several infectious diseases persist at a high level of incidence, occur on a global scale, and can be transmitted between humans either directly or indirectly.
mTOR-activated HCC was associated with a higher level of alpha-fetoprotein and a higher incidence of recurrence [ 7].
With extremely prevalent risk behaviours, the migrant MSM had a high level of HIV incidence, and a serious epidemic of syphilis was found among this subgroup.
In countries with a high level of perinatal care, the incidence of asphyxia responsible for moderate or severe encephalopathy is still 2 3 per 1000 term newborns.
Current Controlled Trials ISRCTN62175998; ClinicalTrials.gov Identifier NCT01241019; EudraCT Number 2010-018627-25 In countries with a high level of perinatal care, the incidence of asphyxia responsible for moderate or severe encephalopathy is 2 3 per 1000 term infants [ 1, 2].
A hypoxia-conditioned medium, which contained a high level of VEGF, significantly reduced the incidence of radiation-induced apoptosis of human umbilical vein endothelial cells in vitro [ 35– 35].
The trend after implementation of screening was estimated under the assumption that screening leads to a higher incidence level that increases at about the same rate as the background incidence did before screening.
These countries have small, relatively isolated populations, and so even a small outbreak of ARF can be calculated as a high incidence level, given relatively small denominators.
Routine decennial vaccination is predicted to lead to only a slightly higher level of costs and a slightly lower incidence, and is optimal in the low vaccine efficacy or high incidence sensitivity analysis.
Breast cancer, a neoplastic disease with high level of incidence and mortality, is the prevalent cancer in females [ 1, 2].
