Sentence examples for a higher deleterious effect from inspiring English sources

A higher deleterious effect of CD68 infiltration was found in HER2 tumors (P = 0.04), while in hormone receptor-positive tumors the main factor associated with worse DFS was a higher CD8 count (P = 0.04).

Experimentally sodium chloride at 2% concentration and higher had a deleterious effect on development of hookworm eggs and larvae [ 31]; seawater contains approximately 3.5% sodium chloride.

Interestingly, PGE2 was found to have a biphasic influence on the development of acid-reflux esophageal lesions; a protective effect at lower doses; and a deleterious effect at a high dose, and both effects were mediated by the activation of EP1 receptors [ 16].

A higher CADD score implies a more deleterious effect caused by the SNP.

Our finding of a potential deleterious effect of higher maternal and infant iron stores on infant growth requires further exploration and suggests a cautious approach to iron supplementation during the antenatal and early infancy periods in populations with low rates of iron deficiency.

In D. melanogaster and other animals, mitochondria are likely major regulators of longevity, although their exact role in aging is not fully understood (Stefanatos and Sanz 2011), and in our controlled crosses, we find some evidence for mitochondrial variant(s) that seem to extend lifespan at low temperatures but have no or a slight deleterious effect at higher temperatures.

Four of the eight variants caused a missense mutation, but only one of these, R18K in ZC4H2, had a high Polyphen-2 score (0.97) suggesting a deleterious effect on protein function (Table  2).

Note that the use of a mechanical mask at deposition temperatures higher than 500 °C may have a deleterious effect on the carrier mobility, as the high oxygen ion diffusion can unintentionally disturb the oxygen equilibrium for realizing high mobility.

However, this hypothesis can be challenged by data showing a deleterious effect of high O2 in patients with severe coronary artery disease and myocardial infarction [ 45, 46].

6 Estrogen plus progestin therapies have shown different results for lipid modification, since these androgenic progestins have a deleterious effect on high density lipoprotein cholesterol; 7 also some progestins are associated with fluid retention which can be associated with edema and breast tenderness and which may impair HT compliance.

Within the soil, high sodium concentration can have a more deleterious effect on soil structure.