Overall, this study showed a rather high (substantial to almost perfect) inter-observer agreement for all three methods investigated, which all seemed to capture the association with breast cancer assessed by both readers.
First, there is to be a new, four-way classification of risks -- "high," "substantial," "moderate" and "low".
Public health is a high profile and substantial operation which deserves a place on the senior management team.
The Department of Homeland Security, through its Customs and Border Protection agency, uses this data to generate a risk rating, and any package with a high rating gets substantial additional scrutiny.
But the EU institutions – a 27-strong commission that is far too big, a European parliament disconnected from national parliaments, and three EU presidents (commission, council and parliament) and a high representative – need substantial slimming down and refocusing to make them fit for purpose.
Chronic major depressive disorder and dysthymia are associated with a high burden and substantial care costs.
Moreover, the mountainous landscape of the middle belt and northern border exhibit a high potential for substantial wind energy.
Effective use of natural materials to fabricate porous carbonaceous structures for anodes of microbial fuel cells (MFCs) has a high potential for substantial cost reduction in MFC.
Although the GVF model has proved effective and has widely been used in image segmentation, it has some disadvantages, such as a high computational cost, substantial noise sensitivity, and an inability to capture and preserve weak edges.
New high-resolution DEMs that do combine a high resolution with substantial spatial coverage provide the opportunity to develop site-specific management alternatives for sensitive or critical source areas at the landscape level.
A high score indicates substantial amino acid identity between the two proteins.
