Sentence examples similar to a high selection stringency from inspiring English sources

With a higher selection stringency, the selection marker gene has to be expressed at higher levels to be sufficient for surviving the selection process.

We reasoned this would require exceptionally high selection stringency given the extent of background phenotypic variation and the presumed genetic uniformity of the clone.

These low rhA1AT titers are obtained despite the higher selection stringency as demonstrated by the relatively higher fold amplifications and the lower selection and amplification efficiencies of the pAID*p vector (Table  2), in contrast to the study by Westwood AD et al. [ 35] where higher selection stringency led to higher recombinant protein titers in serum-containing –HT medium.

Hence, we set a high stringency and calculated the precision (true predictions out of all predictions for essentiality) with a high selection criterion (more than 195 out of 200 votes).

Besides selecting for the presence of the two plasmids based on leucine and tryptophan selection, we employed a high stringency selection of positive protein interactions by using 3 more reporter genes to eliminate potential false positives: histidine, adenine, and Mel1, which encodes alpha-galactosidase for blue/white screening.

Fourth, we have employed a high stringency selection in the YTH analysis by utilizing 4 different reporters to ensure the validity of the data.

We applied a high stringency data selection, keeping only microarray elements for which at least 80% of the measurements within a set of experiments had fluorescence intensity in both channels at least 3-fold over background intensity.

This difference may be due to a difference in selection stringency of both groups.

However, a high stringency within the selection process, typically lends greater confidence to the relevance of those genes identified as differentially expressed in the cancer datasets.

To identify roo elements in the 12 focal Drosophila genomes, we carried out a high stringency and a low stringency search.

These findings suggest that while a high BLAST stringency yields more accurate predictions of sRNA-encoding loci, lowered BLAST stringency may be useful in more sensitively identifying primary sequence conservation of these loci in less closely related species.