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The phrase "a high predisposition to" is correct and usable in written English.
It can be used to describe a strong tendency or inclination towards something, often in a psychological or behavioral context.
Example: "The study found that individuals with a high predisposition to anxiety are more likely to avoid social situations."
Alternatives: "a strong tendency to" or "a significant inclination towards".
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Care dependent and aged persons have a high predisposition to develop dry skin conditions.
Individuals with a high predisposition to violence are more likely to respond to environmental triggers (e.g., social interactions, stressors) with violence, compared with individuals with a lower predisposition to violence (Ferguson and Dyck 2012).
In particular, the MSSA genomes of strains belonging to ST30 showed a high predisposition to be heteroresistant and PVL-positive [ 33].
Mutations in human XPD (also known as ERCC2) mainly cause three clinical phenotypes: xeroderma pigmentosum (XP), Cockayne syndrome (XP/CS) and trichothiodystrophy (TTD), and only XP patients have a high predisposition to developing cancer.
In the case of flat-coated retrievers, which show a high predisposition to developing histiocytic sarcomas, cases and controls were found to have a similar distribution of exon 1 alleles.
BMI1 downregulates the expression of tumour-suppressor genes, such as p16INK4a and p14ARF (Valk-Lingbeek et al, 2004), transgenic mice have a high predisposition to lymphomagenesis, subtypes of human lymphomas harbour BMI1 gene amplification and overexpression and it induces cell immortalisation (Valk-Lingbeek et al, 2004; Raaphorst, 2005).
Similar(53)
Furthermore, results on the network of replies also shows a dual structure: a cluster around the candidate receiving the largest attention from other parties, and another with the movement activists exhibiting a higher predisposition to dialogue with other parties.
Animal models lacking p53 have a higher predisposition to cancer [ 4, 5].
Furthermore, impaired glucose regulation predisposes one to cognitive impairment and AD (2– 4), and insulin resistance may indicate a higher predisposition to AD (5).
In addition, some haplogroups that codify for genes related to the MRC, confer a higher predisposition to develop the OA disease [ 5].
Because men have a higher predisposition to developing coronary artery disease than do premenopausal women, we hypothesized that LDL electronegativity is increased in men and promotes endothelial damage.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com