Exact(2)
Previous efforts in EST sequencing from this species revealed a high level of sequencing redundancy, largely due to very high proportion of mitochondrial genes [ 12, 17].
Due to the high statistical power needed to specifically recognize the reads obtained, the shotgun approach requires a high level of sequencing depth, e.g. the total number of bases sequenced has to exceed largely the total length of the target DNA so that each DNA region is sequenced many times.
Similar(58)
BACE2 is a membrane-bound aspartic protease of the A1 family with a high level of sequence homology to BACE1.
Total of 20 distinct clades were identified and showed a high level of sequence divergence within TIR-NBS and non-TIR-NBS subfamilies.
Comparing the predicted protein with those from other species using a BLAST search tool, we found that it exhibits a high level of sequence identity to effector caspases such as caspase-3 and -7, although it has a caspase recruitment domain (CARD) that is similar to those of initiator caspases such as caspase-2 and -9 (Fig. 1b).
Although sharing a high level of sequence identity between their CP, ArMV is transmitted exclusively by the ectoparasitic nematode Xiphinema diversicaudatum whereas GFLV is specifically transmitted by the nematode X. index.
Despite a high level of sequence identity, CAV21 and PV cause distinct clinical disease typically attributed to their differential use of host receptors.
This family is composed of three isoforms: PIM1, PIM2, and PIM3 that share a high level of sequence homology and exhibit some functional redundancy.
Multiple alignments between BnaABF2 and seven other ABF proteins revealed a high level of sequence similarity among each other (Fig. 1).
PIM1, PIM2 and PIM3 (proviral integration site for moloney murine leukaemia virus) kinases form a three-member subgroup of serine/threonine kinases family, which share a high level of sequence homology and exhibit some functional redundancy.
Since a high level of sequence conservation was observed between the different EUL domains in rice (Additional file 4: Table S3), this analysis was extended with the EUL domains obtained from the different monocot and dicot species.
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