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It is claimed that the particle aggregation methodology may present several advantages, such as combine simultaneously a high interconnectivity with high mechanical properties that are both critical for an in vivo successful application.
In particular, it has been reported that the C(k) distribution of networks with hierarchical structure follows a power-law, with a high interconnectivity among nodes of low degree that decreases as the degree increases [ 18].
While the mRNA levels of the genes encoding for the hub proteins themselves are not affected by EGF, we can detect strong changes in many of the genes directly connecting to them and a high interconnectivity among regulated genes pertaining to each hub's own network.
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PHBV/PAM scaffolds showed a higher interconnectivity than PHBV scaffolds.
The ideal scaffold for use as a transplant not only has good biocompatibility, appropriate mechanical properties, and a well-matched degradation rate [ 3– 5] but also has an appropriate pore size and high interconnectivity to promote cells attachment, proliferation, and bone repair [ 6– 10].
Central node substrates were identified as proteins with a high level interconnectivity within a functional category, which indicates a greater influence a protein has on a phenotypic response.
The regulatory cellular and molecular mechanisms in an organism have to be organized by high interconnectivity to fulfil complex functions, such as signal sensing, transduction and processing, and thereby maintain systemic and cellular homeostasis.
In addition, we are able to define a large EGF dependent gene network using the high interconnectivity observed among the minor pathways regulated by EGF.
They displayed hallmarks of chromothripsis, including a high number of CN switches, alternations between a small number (2−3) of CN states, and high interconnectivity (i.e., connections between regions which are usually far apart on a chromosome) (Stephens et al. 2011; Maher and Wilson 2012; Rausch et al. 2012b).
To achieve tunable pore size with high interconnectivity, the SMP foams were prepared via a refined solvent-casting/particulate-leaching (SCPL) method.
Due to misclassifications of ponds as lakes, associated with the high interconnectivity between irregularly structured open water objects, we used a low edge to area ratio on lakes, to ensure accurate classification of ponds.
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