Used and loved by millions
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
a high dose of
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "a high dose of" is correct and usable in written English.
It can be used when discussing the quantity of a substance, typically in medical or scientific contexts, to indicate a significant amount. Example: "The doctor prescribed a high dose of medication to manage the patient's symptoms effectively."
✓ Grammatically correct
Science
News & Media
Academia
Alternative expressions(19)
a large amount of
an elevated level of
a substantial amount of
a significant quantity of
a lot of
plenty of
a large dose of
a large quantity of
an excessive quantity of
a considerable measure of
a high potential of
a high rate of
a daily dose of
a high significance of
a hefty dose of
a high confidence of
a big dose of
a high accuracy of
a high stability of
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
60 human-written examples
Ms. Malone said she found relief from Dr. Talley, who prescribed a high dose of OxyContin.
News & Media
As a result, the man kept getting a high dose of warfarin.
Academia
A third of the mice received a high dose of NAC in their drinking water.
Academia
Taking in a high dose of mercury is toxic to the human nervous system.
Academia
The emergency contraceptive is actually a two-pill regimen containing a high dose of drugs used in birth-control pills.
News & Media
β-AR blockade in dHipp during retrieval provides long-lasting protection against reinstatement to a high dose of cocaine.
Science & Research
I am on Prozac and antipsychotics; one of my closest friends takes a high dose of Venlafaxine.
News & Media
An ideal cancer treatment would deliver a high dose of drugs to tumor sites while minimizing side effects.
News & Media
If two tests show the CRP level is high, they may prescribe a high dose of a potent statin.
Academia
Wear loss of TiAlN was significantly reduced by a high dose of boron ion implantation.
This included a high dose of OxyContin, a popular brand of opioid pill.
News & Media
Expert writing Tips
Best practice
When discussing medication or treatments, clearly specify the substance and unit of measure involved with "a high dose of" for clarity.
Common error
Avoid using "a high dose of" when referring to non-quantifiable concepts; instead, opt for terms like "a high degree of" or "a significant level of" for abstract measures.
Source & Trust
84%
Authority and reliability
4.5/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "a high dose of" functions as a determiner phrase, modifying a noun to indicate a significant quantity of that noun. Ludwig's examples show it frequently precedes nouns related to medication, substances, or treatments, indicating a substantial amount.
Frequent in
Science
36%
News & Media
35%
Academia
29%
Less common in
Formal & Business
0%
Encyclopedias
0%
Wiki
0%
Ludwig's WRAP-UP
In summary, the phrase "a high dose of" is a grammatically sound and common expression used to denote a considerable quantity, primarily in scientific, medical, and news-related contexts. Ludwig AI confirms its correctness and usability in written English. When using the phrase, ensure clarity by specifying the unit of measure and substance, and avoid overgeneralizing it to non-quantifiable concepts. While alternatives exist, such as "a substantial amount of" or "a significant quantity of", the choice often depends on the specific context and desired level of formality. Therefore, while not always appropriate in informal speech, the high frequency and wide usage of this phrase demonstrate its relevance for a variety of writing applications.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
a large quantity of
Uses "large" as a synonym for "high", providing a more direct and simpler alternative.
a substantial amount of
Replaces "high dose" with a more general term for quantity, applicable in various contexts.
a significant quantity of
Similar to "a substantial amount of", but emphasizes the importance of the quantity.
an elevated level of
Focuses on the level or concentration of something, particularly suitable for abstract concepts.
a concentrated amount of
Emphasizes the density or concentration of the substance.
a potent concentration of
Suitable when referring to a powerful or highly effective substance.
an excessive quantity of
Implies that the quantity is not only high but also potentially harmful or undesirable.
a considerable measure of
A more formal way of expressing a significant amount, often used in technical or scientific writing.
a hefty measure of
Suggests a large and impactful amount.
an intensive quantity of
Highlights the intensity or strength associated with the quantity.
FAQs
How can I use "a high dose of" in a sentence?
You can use "a high dose of" to describe a significant amount of a substance, especially in medical or scientific contexts. For example, "The patient was given "a high dose of antibiotics" to combat the infection."
What can I say instead of "a high dose of"?
You can use alternatives like "a substantial amount of", "a significant quantity of", or "an elevated level of" depending on the context.
Is it appropriate to use "a high dose of" in informal writing?
What's the difference between "a high dose of" and "a large dose of"?
The phrases "a high dose of" and "a large dose of" are largely interchangeable and convey the same meaning. The choice between them often comes down to stylistic preference.
Editing plus AI, all in one place.
Stop switching between tools. Your AI writing partner for everything—polishing proposals, crafting emails, finding the right tone.
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
84%
Authority and reliability
4.5/5
Expert rating
Real-world application tested