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In 1993, a heritable resistance to APC was detected by Dahlbäck et al. and associated with familial thrombophilia.
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The CRISPR system confers to prokaryotes a highly adaptive and heritable resistance to foreign genetic elements such as plasmids and phages [ 30– 30].
Loblolly pines have shown a pattern in more highly heritable resistance to fusiform rust similar to that we observed, whereby nursery assays identified field-resistant families, but not all field-resistant families were resistant in the nursery (Powers and Kuhlman 1987; Isik et al. 2008).
Several mathematical models have been developed to describe the likelihood of development of heritable resistance, e.g. a mutation, and its subsequent spread in a population; see e.g. Abel zur Wiesch et al. (2011), Day and Bonduriansky (2011).
A very interesting and, in my opinion, promising hypothesis on the mechanism of heritable resistance to pathogens in arthropods.
All progenies from self-fertilized transgenic plants had strong and heritable resistance to RGDV infection and did not allow the propagation of RGDV.
Once genetic resistance has evolved, control becomes unnecessary, because the avian population is protected against influenza re-emergence by heritable resistance.
Ross et al. [ 16] reported the first evidence for heritable resistance to haemonchosis in sheep.
These mechanisms involve new genetic changes in the pathogen leading to heritable resistance.
Overall, our results show that transgenic plants based on the multi-target dsRNA approach can confer heritable resistance.
In addition to acquiring the heritable resistance to the acute teratogenic effects of PAHs, ER fish appear to have concomitantly developed resistance to chronic effects, including cancer.
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