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The dcr mutation appears to represent a heritable model of vascular disease, with particularly severe pathology in the brain.
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The rs2229238 T allele contributed to a reduced risk to TB in recessive heritable model (OR, 0.53; 95% CI, 0.35 0.78).
Therefore, we have developed and characterized a heritable zebrafish model of NF1 that exhibits clinical hallmarks of the disorder, including nervous system defects and increased susceptibility to tumorigenesis.
This review discusses the relative utility of mouse models in which a heritable or non-heritable (acquired) manipulation has been used to model a specified trait of a human neurological disorder.
The rpoS gene expression is modeled as a heritable trait.
In the framework of cultural evolution, several models have addressed the role of a heritable environmental state on phenotypic resemblance between relatives.
In that case our model presents a specific dynamic explanation of how a heritable environmental state is able to cause heritable epigenetic modifications of a phenotype.
Their model would apply equally well to cultural traits or a heritable environmental state.
When non-random mating for a heritable trait is present but this is not specifically included in the twin model, heritability estimates may be downwardly biased.
Here we develop a Bayesian approach to model twin data with dichotomous outcomes, estimate case-wise concordance rates and test for the presence of a heritable component.
The evidence, they concluded, strongly suggested a "heritable component".
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