Sentence examples for a heightened dependence from inspiring English sources

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Several lines of evidence suggest that cancer cells have a heightened dependence on mechanisms of protein homeostasis (proteostasis) [ 2], including the UPS.

Cancer cells may have a heightened dependence on protein degradation pathways, as their numerous genomic mutations often effect an imbalance in protein levels or the production of defective proteins.

In theory, this creates in cancer cells a heightened dependence on protein quality-control (PQC) mechanisms, including protein chaperones, the UPS, and autophagy [ 9- 12].

Similar(57)

Due to an increase in consumerism, heightened dependence on technology, and an overall world population growth, more and more minerals and metals need to be extracted from the earth's surface as shown in Figure 1.

The proteotoxic crisis hypothesis suggests the attractive prospect that it may be possible to attack a broad range of human cancers by taking advantage of their presumed heightened dependence on PQC pathways.

Given that tumours may be hyperdependent on nutrient supplies and may scavenge extracellular protein to ensure sufficient amino acid availability, the VCP inhibitor-associated heightened dependence on amino acid supplies may be clinically relevant.

From its relatively novel perspective, our study confirmed and extended several findings using other approaches, suggesting that male gender, stressful life events, dysfunctional family structure, anxious personality, and impulsivity are associated with a heightened risk for drug dependence (32).

Currently ranking first in global opioid analgesic consumption [ 9], Canadians are at a heightened risk for opioid abuse and dependence, giving rise to a major public health crisis [ 10].

The child thus faces a heightened risk of sexual assault.

Our unreality is operating at a heightened pitch.

Then it is set in a heightened, created world.

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