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Unless the neuronal group has the capacity to revert to its original state given a harmful variation, in which case it is effectively behaving as a 1+1 Evolutionary Strategy [27], there is the potential that good solutions are lost.
If a harmful variation is generated around the Mhc gene via the hitch-hiking effect, then it is likely to be selected against by genetic recombination.
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Reducing unintended, and particularly harmful, variation is therefore a key improvement strategy.
Deliberate quality control efforts can reduce harmful variation in practice, decrease adverse events and prevent litigation [ 39- 41].
Enrichment analysis of GO terms was performed for all the genes containing at least one harmful variation and GO terms were considered significant at FDR < 0.01.
Because genes come in pairs (alleles), a person with potentially harmful variations in both alleles is presumably at even greater risk than someone with a single variation.
Darwin himself consistently refers to natural selection as a power of preserving advantageous, and eliminating harmful, variations.
Achieving such a system in the ICU will require constant vigilance in order to minimize potentially harmful variations in care.
The exoperidium may help to protect the maturing gleba of late-fruiting species from harmful variations in temperature or humidity, or from insect predation.
In total, 4.76 % of the harmful variations were present in CGC genes.
Among the harmful variations, the C > G substitutions are less frequent in most of the cancers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com