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The phrase "a harmful effect" is correct and commonly used in written English.
It is typically used to indicate negative consequences or outcomes. Example: The use of pesticides in farming has had a harmful effect on the environment and has led to the decline of pollinator populations.
Exact(60)
"It could have a harmful effect on our economy".
ABC's descent had had a harmful effect on the stock fortunes of Disney.
Obsessively ruminating about how miserable life is, studies show, can have a harmful effect on health.
Local businesses have been quietly lobbying against the legislation, fearing it may have a harmful effect on recruitment.
"It feeds into a fear of rape and sexual violence and has a harmful effect on broader issues of equality".
"It is so inaccurate on its facts that it's had a harmful effect, rather than no effect".
OPEC continued to raise oil prices &this has had a harmful effect on our economy & balance of payments.
Exposure to noise has a harmful effect on the auditory health of workers.
The effect of warm waters on Atlantic cod likely occurs because of a harmful effect on larvae and juvenile fish.
It argues that allowing guns in classrooms could have a harmful effect on academic freedom because professors will be wary of broaching controversial subjects.
Garrison, the American women's coach, hinted that the coming Open could have had a harmful effect on the whole team at Athens.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com