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In a hallmark of conversion narratives, the original mania reproduces itself as a mirror image: in the old days, hyperbolically anxious; in the new, hyperbolically anxious to enumerate the old anxiety.
It promotes a series of molecular transitions that are a hallmark of conversion from the PTC recognition complex to the mRNA degradation complex resulting in NMD activation.
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The perfect alignment between the V sequences and the corresponding germ line sequences are inconsistent with the insertion of V sequence fragments, a hallmark of gene conversion.
A hallmark of the prion diseases is the conversion of the host-encoded cellular prion protein (PrPC) into a disease related, alternatively folded isoform (PrPSc).
A hallmark of the common Alzheimer's disease (AD) is the pathological conversion of its amphiphatic amyloid-β (Aβ) peptide into neurotoxic aggregates.
The conjugation of the soluble form of MAP1LC3 (MAP1LC3-I) with phosphatidylethanolamine and conversion to a nonsoluble form (MAP1LC3-II) is a hallmark of autophagy; thus we examined the expression of MAP1LC3B-II formation.
The conversion of soluble peptides and proteins into polymeric amyloid structures is a hallmark of many age-related degenerative disorders, including Alzheimer's disease, type II diabetes and a variety of systemic amyloidoses.
We showed a time-dependent conversion of LC3BI into its autophagosome-bound form LC3BII, which is a hallmark of autophagy and we observed the presence of autophagosomes in photosensitised HeLa cells, as well as MDC-positive vacuoles.
To investigate whether NDV/FMW interacts with the autophagy machinery in drug-resistant A549 and parental cells, we first examined the conversion of LC3I (cytosolic form) to LC3II (autophagosome-bound lipidated form), a hallmark of autophagy [ 37].
The conversion of PrPC into an abnormal conformer, PrPSc, prone to aggregation, is a hallmark of prion diseases.
The conversion of this host-encoded protein to an abnormal, partially proteinase K resistant, isoform is a hallmark of most TSEs and PrP is the only known constituent of mammalian prions [ 3].
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