Sentence examples for a hallmark in the development of from inspiring English sources

Also, loss of the epithelial marker E-cadherin is a hallmark in the development of TKI resistance [ 14].

Although the acquisition of genomic alterations has been recognized as a hallmark in the development of cancer, the sequence and role of specific alterations is less clear [ 6].

Myofibroblasts accumulated in clusters (fibroblastic foci) are considered the hallmark cells in the development of lung fibrosis [ 14].

VSMC and macrophage proliferation within the artery wall is a major event in the development of the atherosclerotic lesion, a pathological hallmark of coronary artery disease.

IL-1A and IL-1β play a crucial role in the development of AD and PD, the pathogenic hallmark of which is CNS inflammation.

Angiogenesis is a general hallmark of cancer; therefore, the inhibition of tumor-derived angiogenesis is considered to be an attractive target in the development of anti-cancer agents.

Angiogenesis, the development of new blood vessels following the proliferation of the endothelial cells of preexisting vessels, is regarded as a hallmark in cancer development 1.

Abundant extraneuronal deposit of amyloid-beta (A β) is the major pathological hallmark and plays an early important pathologic role in the development of AD.

The major pathological hallmark of AD plays an early and important pathologic role in the development of AD.

The increase of acylglycerols should therefore be considered the hallmark leading to the development of the fatty liver observed in the ob/ob mice [ 42, 43].

Transplantation onto the back of immunocompromised rats consistently resulted in the development of melanoma, displaying the hallmarks of their parental tumors.