The phrase "a guess about which" is correct and usable in written English.
It can be used when referring to a specific subject or topic that one is making a guess about.
Example: "She made a guess about which candidate would win the election."
Alternatives: "a speculation regarding" or "an assumption about".
The top layer makes a guess about which senone it thinks the system has heard.
Before each flu season, epidemiologists monitor the rapidly evolving flu virus over a period of months, and the World Health Organization (WHO) makes a guess about which three strains are mostly likely to spread.
Adults had to make a guess about which of two objects in a pair would sink faster.
If subjects did not think that the photo had been manipulated, we asked them to make a guess about which area of the image might have been changed.
Even if there were would be no stratification but inbreeding, the inbreeding coefficient could also allow a guess about which population was included.
The company's product, Instinctiv Shuffle, is an iPhone application (jailbroken iPhones only, for now), that watches your listening habits to make a smart guess about which song you'll want to listen to next.
The distribution information provides a rough metric for the users to make an initial guess about which number representations to use.
In the role of art detectives, students can analyze other works by Giotto and Cavallini, and make an educated guess about which painter they think was the "primary creative force" behind the "Legend of St. Francis" fresco cycle.
But it has certainly not been the only occasion upon which observers have attempted to make an educated guess about which school grade the Republican nominee should transfer into.
Without computer help, this match-up process takes 20 to 40 hours per patient: The expert looks at a list of around 100 of the patient's suspicious-looking mutations, makes an educated guess about which one might cause disease, checks the scientific literature, then moves on to the next one.
To find out, molecular oncologist Masanori Hatakeyama of Hokkaido University in Sapporo, Japan, and his colleagues first made an educated guess about which human protein CagA interacts with inside stomach cells.
