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This could mean that selection tends to purge mutations located in highly expressed genes because they lead to a greater waste of resources (Barton et al. 2010; Vieira-Silva et al. 2011).
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It would also be a great waste of St Paul's.
The couple thought the foyer was a great waste of space.
Behind these figures is a great waste of human resources, and a lot of human misery.
"The walls seemed a great waste of stone and mortar," he said.
As Henry wanly observes at one point in the book: "Travel can be a great waste of time".
Many classic recipes say to butter the mold once, put it in the freezer and then butter it again -- a great waste of time.
Forcing the government to take scientists off their lab benches to testify in court is a great waste of time and money — and unlikely to change the outcome of many, if any, trials.
The current manufacturing process is conducted with much machining work including drilling the hollow, which results in a great waste of material.
At the end of the day I am left with the impression that this has been much ado about very little and a great waste of energy, time and money.
This reveals that most network devices and links stay idle or underutilized most of the time, but an idle device consumes up to 90% of the power consumed at full loads [6], which leads to a great waste of energy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com