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The phrase "a great waste of" is correct and usable in written English.
It can be used to express that something is considered to be a significant loss of resources, time, or potential.
Example: "Leaving the project unfinished is a great waste of talent and effort."
Alternatives: "a significant loss of" or "a considerable misuse of".
Exact(15)
It would also be a great waste of St Paul's.
The couple thought the foyer was a great waste of space.
"The walls seemed a great waste of stone and mortar," he said.
Behind these figures is a great waste of human resources, and a lot of human misery.
As Henry wanly observes at one point in the book: "Travel can be a great waste of time".
Many classic recipes say to butter the mold once, put it in the freezer and then butter it again -- a great waste of time.
Similar(42)
This could mean that selection tends to purge mutations located in highly expressed genes because they lead to a greater waste of resources (Barton et al. 2010; Vieira-Silva et al. 2011).
Likewise, pumping water into natural aquifers for seasonal storage tends to be much cheaper than building a big dam, and prevents the great waste of water through evaporation.Even when water is scarce, it is often squandered.
It is not possible to estimate this great waste of talent, of potential.
If that is the only game he plays for Liverpool, Ilori will prove an even greater waste of money than he has so far.
In mental health, the duration of new appointments is usually longer than follow up appointments [ 7] and this makes non-attendance for new appointments an even greater waste of already stretched resources and delaying contact with services [ 6].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com