Sentence examples for a great difference was from inspiring English sources

There was no difference of temperature between both samples at 45 °C of water supply, but a great difference was shown at 75 °C.

According to a study of the nyala in South Africa, Mozambique, Malawi and Zimbabwe, a great difference was marked among the gene frequencies at three microsatellite loci.

Again a great difference was observed among the LAB strains in their capacity to up-regulate the expression of MHC class II and co-stimulatory molecules (CD86, CD40) (Fig. 3).

Despite this apparent similarity in survival, a great difference was evident in the capacity of both products to sterilize the thighs of survivors after 4 days of treatment: 100% mice in the innovator group had sterile thighs, while 0% achieved this goal after generic treatment, leaving approximately 4 log10 CFU of P. aeruginosa per thigh.

A great difference was observed in the mast cell degranulation in the colonic mucosa in response to SEB stimulation between the groups with UC only and UC-CRS ex vivo.

Anyway, very often a great difference is experienced between predicted performance of building elements as calculated using the methods prescribed in technical standards, and the one considering as-build conditions, particularly in the field of building renovation where the envelope thermal transmittance value must be measured on site.

A great difference is also, of course, that C is a 17 × 17 matrix leading to 17 eigenvalues and implying that analytic solutions are impossible in practice.

So if one puts the rope over still more, a great difference is made by a few pulleys, so that supposing a weight of four minae is being borne by the first, much less is being borne by the last.

The reason the FDA action will make a modest rather than a great difference is not because it is unimportant, but rather because it is late in the game.

However, a greater difference was evident between the patients and the health care providers.

A greater difference was seen in the number of genes down-regulated by BCG and PPD.