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"One of the humbling things about this field is that there were great minds who worked on it but they haven't made a great dent in the problem," said Dr. Dyann F. Wirth, a malaria researcher at the Harvard School of Public Health.
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That could finally start putting a more substantial share of the 11.3 million idle Americans back to work and make a greater dent in the unemployment rate, which ticked down to 7.2 percent last month.
"My back feels great," Dent said.
The federal $2,000 credit by itself doesn't make a big dent in the far greater cost of a photovoltaic system, so you'll need a generous state incentive to make that investment pay off.
"We had a great year in political merchandise, but it didn't make a big dent in our sales number".
The competitive pressure from Internet telephony has forced AT&T to lower its prices for telecommunications services, but some say the technology will make an even greater dent in AT&T's armor.
And take great care not to hide it somewhere that she can accidentally swallow it; that'll put a big dent in the occasion.
That would make a big dent".
"We've had huge dents in the armor," Collins said, "and this is a big dent".
That would make a big dent in that £22bn".
You put a big dent in communications problems with EMR.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com