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The phrase "a great decrease in" is correct and usable in written English.
It can be used when discussing a significant reduction in quantity, size, or degree of something.
Example: "There has been a great decrease in the number of reported cases this year compared to last year."
Alternatives: "a significant reduction in" or "a substantial decline in".
Exact(37)
In developed countries where H. influenza vaccine is used, there has been a great decrease in serious infections and deaths.
"I think it would lead to a great decrease in the number of lemon law claims that would be filed by consumers, and a huge decrease in the number of class-actions that could be filed by dissatisfied customers against manufacturers for product defects," she said.
A great decrease in the ATP content was also seen under Al stress.
As laser fluence is increased, AFM results show a great decrease in the surface roughness of carbon nitride films.
In addition, most ribosomes dissociated at the stop codon of ORF1, followed by a great decrease in the expression of mCherry in ORF2.
(5) An increase in the surface recombination mainly induces a great decrease in the J sc (V oc) for the low (high -N d SiNWA phigh -Nctrode.
Similar(22)
News item: Older adults who say they've had a life-changing religious experience are more likely to have a greater decrease in size of the hippocampus, the part of the brain critical to learning and memory, new research finds.
A greater decrease in the sound reduction performance is found in soft resilient materials.
Inadequate pelvic collateral circulation that leads to a greater decrease in cardiac output may be causative in the syndrome.
The average crab experienced a greater decrease in predation risk when the predator was small or slow moving.
However, the one-variable intervention was found to lead to a greater decrease in children's EB at follow-up.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com