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The phrase "a grave problem in" is correct and usable in written English.
It can be used to describe a serious issue or concern within a specific context or field.
Example: "The report highlighted a grave problem in the healthcare system that needs immediate attention."
Alternatives: "a serious issue in" or "a critical concern in".
Exact(11)
"Prolonged isolation of individuals in jails and prisons is a grave problem in the United States," the statement said.
In the second half of the 12th century, heresy had become a grave problem in southern France.
Independent human rights monitors are not allowed into Turkmenistan, but Human Rights Watch notes that torture is still a "grave problem" in its prisons.
There is little doubt that youth unemployment is a grave problem in Europe, a result not only of weak economic growth but also of inflexible labor regulations that make it hard for newcomers to break into the work force.
As ASCA explained then, "prolonged isolation of individuals in jails and prisons is a grave problem in the United States". Today, a national consensus has emerged focused on limiting the use of restricted housing, and many new initiatives, as detailed in the report, reflect efforts to make changes at both the state and federal levels.
Municipal solid waste (MSW) management is a grave problem in most of the urban cities in India due to generation of its huge quantity and non-availability of suitable and cost-effective technologies for treatment and disposal (Kumar et al. 2009; Bundela et al. 2010).
Similar(49)
"If this problem is not controlled it could once again become a grave problem as it was in the 80s and 90s," he said.
The attacks brings to light a grave problem facing America: the Shiite revival in Iraq since the fall of Saddam Hussein has reinvigorated a Sunni militancy that in turn threatens peace and stability in a broad swath of Asia from Pakistan to Lebanon.
We have a grave problem of militancy and the attacks in Mumbai are a grim reminder of the endless possibilities of terror.
The lack of affordable housing in New York City is a grave problem ["Keeping Young Teachers Close to Work," Feb. 22].
Mortality among pregnant women is a grave problem: Lack of health care access results in complications and even death for either mother or baby.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com