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Sterility, therefore, was widely regarded as a grave misfortune.
Certainly this would be a grave misfortune for the person.
Similarly, it would be a grave misfortune for you if your spouse came to despise you, but for some reason pretended to love you, so that you underwent no loss of pleasure.
In every society there are those tortured by their own mind--individuals born mentally ill or afflicted by mental illness after suffering a grave misfortune.
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As an emergency room physician, an Army veteran who was deployed to a combat support hospital in Baghdad in 2005, and a biomedical researcher in the field of cardiac-arrest resuscitation, I have been and am, on a daily basis, a witness to grave misfortune.
Human beings with radical cognitive disabilities suffer "grave misfortune" but not reduced status if they are not able to share in the distinctive forms of our common life in which their embodiment has "embedded" them.
Homer purchases a severed monkey's hand that will grant four wishes, despite the vendor's warning that the wisher will meet with grave misfortune.
Then there is Citadel Investment Group, the hedge fund known as a grave dancer for its ability to profit from the misfortunes of others.
This is a grave error.
This is a grave matter".
That's not a grave".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com