Herein, we have the idea that a good hypothesis will explain a plethora of effects including many not originally under investigation.
"It's a good hypothesis, but it's not proven," Dr. Ryan said.
"That's enough similarities that it's a good working hypothesis that they're parts of the same thing," he says.
Thus, T1 is a significantly more likely organismal phylogenetic tree than the alternative topologies (T2 and T3).Together, these results indicate that the true phylogenetic tree exists, and provide a good explanatory hypothesis basis for the evolution of the genes under study.
Slides 3-6 are a good narrative of hypotheses validated, invalidated and refined during the week.
I should also have a good idea of the hypothesis and context within the first few pages, and it matters whether the hypothesis makes sense or is interesting.
My longwinded explanation (left on the ABC News cutting room floor, understandably and thankfully) was this: absent any clear-cut exogenous variable or variables accounting for the decline, it behooves us to attribute, as an operational hypothesis, a good part of the drop-off to women's individual and aggregate choice, plain and simple.
Experimental quantification of transmission [30], [31] of geographical isolates under different conditions (e.g., host density, super-infection vs. co-infection) would provide a good test of this hypothesis.
The kinome of E. cuniculi, consisting of only 32 protein kinases (29 ePKs and 3 aPKs), is a good illustration of this hypothesis.
This finding is a good example of indirect hypothesis generation that can come from using such large data-set producing tools.
