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Microdissection has been applied widely to increase the fraction of tumor cells in a given specimen in order to enhance the sensitivity of dideoxy sequencing.
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And who cares whether a given specimen belongs in this phylum or that?
Thus a given specimen could be included in two investigator's approved datasets (one frozen tissue, one fixed tissue), and could also be included in a tissue microarray.
Most molecular assays such as qPCR and pyrosequencing lack the capability to simultaneously detect cooccurring single nucleotide polymorphism (SNP) mutations in different genes in a given specimen [ 73].
When >40% of carcinoma cells in a given specimen were stained more intensely than the normal epithelium in the same section, the sample was classified as FAKoverexpression (FAK.
When more than 80% of carcinoma cells in a given specimen were positively stained as well as normal epithelium in the same section, the sample was classified as TIMP-3 preserved (TIMP-3 ; when less than 30% were stained, as TIMP-3 reduced (TIMP-3 ; and when 30 80% of cells were stained, as TIMP-3 moderate (TIMP-3.
Although fission could easily explain the coexistence of low-frequency haplotypes that differ in one or a few substitutions in a given specimen (Additional file 1: Figure S1), the origin of heteroplasmic individuals that simultaneously present haplotypes A, B and C is difficult to envision.
A confirmed laboratory diagnosis was offered to our clinicians when HSV-1 was isolated in culture and/or viral antigen was detected in a given specimen.
The surface of the blue staining in a given specimen was expressed as a percentage of the brown area (HBME-1-related) in a corresponding section which was treated as 100%%.
Beyond a further observation on the so-called lateral inertia confinement effect, special attention is paid to the transient shock wave effect and the propagation of material failure when a specimen is loaded with a strain rate exceeding a theoretical limit for a given specimen size, i.e., in the "excessive" strain rate regime as referred to in this paper.
In addition, when ⩾20% of the tumour cells in a given specimen were positively stained for N-cadherin, the sample was classified as N-cadherin-positive.
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