The phrase "a given modification" is correct and usable in written English.
It can be used when referring to a specific change or adjustment that has been identified or specified in a particular context.
Example: "In the context of software development, a given modification can significantly impact the overall performance of the application."
Alternatives: "a specific alteration" or "a particular change".
A further complication is the propensity of ubiquitination complexes to generate chains of varying lengths at a given modification site in vivo, making detection of ubiquitination by traditional size separation techniques challenging.
As previously observed [ 16, 17], the kinetic signatures for a given modification varied slightly depending on the surrounding sequence context.
In these cases, the relative abundances of the MS/MS fragment ions characteristic for a given modification site were used to calculate the DMBNHS modification rate constant.
By using affinity-purified autoantibodies against post-translationally modified proteins, it should be feasible to capture a spectrum of antigens expressing a given modification.
For our study, we looked for regions that overlap ≥ 1 nucleotide since SYT-SSX2 interacts with large protein complexes, and a 1-base overlap suggests close proximity to a given modification.
Information on the presence of a given modification in RNA was essentially extracted from the RNA modification database [ 174], the tRNA database [ 4], the small rRNA modification database [ 3] and the 3D ribosomal modification map database [ 14] (for corresponding http, see above in Introduction section).
Using a bottom-up strategy effectively destroys information on how those individual chemical modifications are related, meaning researchers may be able to see that given modifications are present, but are largely blind to their interplay and stoichiometry.
Despite the positive overview of SFS given, modifications were recommended for future delivery.
Here, the numbering of the specific organisms is given; modifications present in A,B,E are in bold; modification that appear specific to H. volcanii/H.
For a given histone modification type, the histone modification variation score (HMV) for a given TF in each of the 4 blood cell lineages was calculated using the formula: Ci represents a specific blood cell lineage and is characterized by discrete values for the three histone marks.
We use the term "broad modification" to denote long regions of chromosomal space in which there is a given epigenetic modification present continuously (>50 kb), as opposed to focal regions of modification ("peaks") in a promoter or other region.
