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Distinguishing which chromosome of a pair a given linkage group belongs to is difficult.
A polyubiquitin chain of a given linkage type signifies a specific type of functional outcome.
This was applied in some particular cases when the LOD curve of the single QTL genome scan method displayed two distinct LOD peaks for a given linkage group.
Markers showing segregation distortion were included in the final map if their presence did not alter surrounding marker order in a given linkage group.
Distorted markers were retained for mapping, if their presence did not alter the surrounding marker order in a given linkage group (LG).
Leveraging experimental mouse crosses such as an F2 intercross has limitations when it comes to identifying the causal gene driving a given linkage.
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Methods that are optimized for computational speed that also correct for multiple tests appropriately given linkage disequilibrium and non-independent multilocus models under consideration are needed to effectively search the genome for gene-gene interactions.
That is, if a gene influenced another gene via a given functional linkage, then the influenced gene would rarely reciprocate along the same functional linkage.
Thus, when correcting chicken sequence assembly errors by RH mapping, we find that all markers from a given quail linkage group correspond to one chicken chromosome.
The confidence scores associated to each functional linkage provided by the original STRING and PROLINKS databases were re-scored according to the following criteria: STRING provides unified scores representing the confidence of a given functional linkage.
Genomically linked amphioxus Akr1 genes are found only within a given clade: linkage groups Akr1_2, 4, and 6 and Akr1_3 and 5 branch within the same clade; Akr1_7, 8, 9, 10, and 12 are also grouped in the tree; Akr1_14 and 16 as well as Akr1_15 and 17 together establish one of the four well-supported clades (table 1).
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