Sentence examples for a given gene sequence from inspiring English sources

In this setting, two or more mRNA populations are labeled with separate fluorescent signals, combined and then used to probe microarrays containing cDNA products or oligonucleotides corresponding to a given gene sequence.

The bioethics commission, chaired by Amy Gutmann, president of the University of Pennsylvania, argues that physicians, researchers, and companies marketing DNA tests need to reframe how they think about all of this: While of course no one knows what will be buried in a given gene sequence, the fact that ancillary findings may be part of it should hardly be a surprise.

It is sometimes supposed that a given gene sequence, for instance, should be expected always to code for the same (set of) function(s), and a protein always to perform the same function(s).

For a given gene sequence, DroshaPSP first determines the hairpin structure with the prediction model HairpinSVM, and then identifies the Drosha processing sites of the hairpin structure with the prediction model DroshaSVM, which integrates the structure, sequence and entropy information.

In addition, to control for the differences in detection efficiency between spots, each probeset (the collection of probes designed to interrogate a given gene sequence) was normalized to its median across all chips or arrays.

A few bioinformatics web tools have been developed to search for specific CRISPR target sites in a given gene sequence [ 14, 17– 19]; however, they mainly focus on analyzing the quantity of off-target sites in the genome and their distributions in the protein-coding regions.

MSP distinguishes unmethylated from methylated alleles of a given gene based on sequence changes that are produced following bisulfite treatment of DNA, which converts unmethylated cytosines to uracils, while leaving methylated cytosines unaffected.

However, CEGMA outputs a predicted protein sequence for each gene, and we note that for a given species and a given gene, the protein sequences derived from different assemblies capturing the gene were largely identical, suggesting that most genes were 100% present and accurate (Additional file 2: Figure S5).

Second, "promoter analysis" can be employed to analyze TFBSs, CpG islands, tandem repeats, the presence of a TATA box, CCAAT box, or GC box, statistically over-represented sequence patterns, GC content (GC%) and DNA stability in the promoter sequence of a given gene ID or a novel promoter sequence.

Secondly, it applies "Promoter analysis" to analyze the TFBSs, CpG/CpNpG islands and tandem repeats in the promoter sequence of a given gene ID or a novel promoter sequence.

MSP distinguishes unmethylated alleles of a given gene based on DNA sequence alterations after bisulfite treatment of DNA, which converts unmethylated but not methylated cytosines to uracils.