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When monoclonal ANAs and non-ANAs generated from a genetically simplified mouse model of lupus, B6.Sle1, were recently compared, the ANAs exhibited three sequence motifs in their immunoglobulin heavy chains, including increased cationicity in CDR3 ("motif A"), reduced anionicity in CDR2 ("motif B") and increased aspartate at H50 ("motif C").
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Even that route, he added, is a bit simplified.
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Such a classification simplified the modeling procedure (Table 2).
The revolutionary technology vastly simplifies the editing of genes, and has triggered many debates about whether its plant products should be considered a genetically modified organism (GMO) and subject to regulation.
The revolutionary technology vastly simplifies the editing of genes, and has triggered many debates about whether its plant products should be considered a genetically modified organism and subject to regulation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com