This lead emerged from a long argument between three colleagues as to whether a genetic system or a cell membrane came first in the development of life.
A genetic system of the kind proposed by Dobzhansky can change rapidly, in response to natural selection, if environmental conditions should change.
Other reptiles have a genetic system which can be overridden by an environmental signal.
Herein, we deploy a genetic system to starve cells of an essential ribosomal protein, which results in the accumulation of assembly intermediates that are competent for maturation.
A genetic system to display proteins as their active and functional forms on the cell surface of yeast, Saccharomyces cerevisiae, has been exploited.
Herein we developed a genetic system that exploits and directs the most abundant Tg-miR-60a for loss-of-function analyses in T. gondii.
We took advantage of the modular structure of the catalytic domain of CyaA to design a genetic system that can detect protein-protein interactions in Escherichia coli.
The approach, dubbed Synthetic Cellular Recorders Integrating Biological Events (SCRIBE), relies on retrons which make up a genetic system found naturally in some bacteria that produces single-stranded DNA that the bacteria normally use to alter their host.
We have developed a genetic system we call "thermorecovery" that allows us to lyse cyanobacterial cultures and hydrolyze membrane lipids to release free fatty acids (FFAs), a biofuel precursor.
We engineered a genetic system to express high levels of recombinant Pseudomonas aeruginosa rhodanese (r-RhdA) in Escherichia coli, and used this organism to test the role of r-RhdA in cyanide detoxification.
As students could choose which model they wanted to work with, the whole of Phase(x) could be viewed as an organism where, as in a genetic system, only the "fittest" works survived.
