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In CD, bacterial translocation, with subsequent generation of strong systemic response is paramount and involves a generalized increase of IgG against commensal intestinal microbiota [22].
However, mitochondria can undergo a generalized increase of permeability of the inner membrane, called permeability transition.
Since CoHb has no oxygen carrying capacity, its presence causes a generalized increase of the Hb level similar to those observed in adults.
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The present results demonstrate not only that this area shows a generalized increase to the degree of familiarity and autobiographical salience but also that this region follows the structural aspects of the music.
Thus, the net result of activation, of nociceptive intracranial dural structures, and altered (dysfunctional) descending modulation of central trigeminovascular neurons, in headache, is due to an altered perception of craniovascular inputs, and also a generalized increase in sensitivity of other sensory inputs, via the modulation by these same brainstem nuclei.
To summarize the results (Table 6), we found that in the acute phase of the model (Days 0 to 5), and before evidence of any cartilage lesions, there was a generalized increase in expression of both chondrogenic and fibrogenic genes in both tissue compartments (presumably a direct anabolic response to TGFbeta1 injection).
The western blotting results revealed a generalized increase in expression of the tested inflammatory markers in cells transfected with mutant TNFR1 (comparedmpared with cells transfected with WT TNFR1 (Fig. 2A and B).
In turn, these reductions may have also resulted from a generalized increase in the severity of colonic inflammation caused by the deficiency of PPAR γ in T cells, as pro-inflammatory cytokines can inhibit Krebs cycle activity [ 48].
Difference in UGA weight was likely due to more advanced/aggressive tumors and not to a generalized increase in body weight of TRAMPJα18−/− mice.
Elemental X-ray microanalysis of myopic form deprived (FD) chick retinas has shown an increase in atomic abundance of K, localized to the vicinity of the sub-retinal space (SRS, RPEE and photoreceptor outer segments, and a generalized increase in the abundance of Na and Cl across the retina, RPE and choroid.
There is a generalized increase in the variation of miRNA abundance with age, consistent with a generalized increase in stochastic dysregulation.
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