Exact(3)
The failure of these B cells to respond to CD40-mediated activation could not be attributed to a generalized deficiency in B cell activation because IL4 induced normal up-regulation of CD23 and CD25 expression.
Impairment of mitochondrial antioxidant enzymes (e.g., manganese-dependent SOD) results instead in a generalized deficiency of the RC, including the iron-sulfur cluster-containing enzymes (complexes I, II, and III) and the Krebs cycle enzyme aconitase [28].
The brain was small (weight 31 g, expected 45 g) and had a generalized deficiency of neuronal migration with neurons seen diffusely through the mantle (thus no layers), a small amorphous group of neurons in the area of the hippocampus, severe dilatation of the third and lateral ventricles and absent corpus callosum.
Similar(57)
The viability of uninfected macrophages steadily decreased during 7 days of culture and there were no significant differences in the death rate among the various types of cells, demonstrating that the TLR KO macrophages do not have a generalized survival deficiency (Figure 9 A).
Diabetes affects zinc homeostasis [ 8] resulting in hypozincaemia, hyperzincuria and, most likely, a generalized zinc deficiency [ 2, 9, 10].
Additionally, a degraded adaptive response in autism was recently demonstrated in autism in an amplitude discrimination task, and it was concluded that a generalized GABA deficiency could also account for this behavior [ 54].
This is probably an important factor contributing to the aforementioned generalized deficiency in web usability.
This global down-regulation across many brain regions, particularly in the cerebral cortex including the STG, may contribute to the generalized deficiencies seen in individuals with schizophrenia, such as poor performance on cognitive tasks, reduced MMN, pre-pulse inhibition (PPI) and eye-tracking dysfunction.
The levels of both of these lipids are decreased in brains of patients suffering from a generalized peroxisome biogenesis deficiency (Zellweger syndrome spectrum) and in AD.
The levels of both of these lipids are decreased in brains of patients suffering from a generalized peroxisome biogenesis deficiency (Zellweger syndrome spectrum) [ 30] and in AD [ 15, 18, 19, 29, 34].
To remedy these two deficiencies, a generalized nearest-neighbor matching function based on a fuzzy inference system is proposed.
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