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However, neuroticism is a general risk factor associated with many forms of psychopathology, such as anxiety, eating, and personality disorders.
PTPN22 is therefore likely to be a general risk factor for the development of autoimmunity.
The results therefore suggest that disturbed balance in the homeostasis of type 1 collagen is a general risk factor.
– The study by Dragsbæk and coworkers suggests that increased turnover of collagen type-1 is a general risk factor for all-cause mortality.
Nonetheless, our analysis suggested victimization as a general risk factor for anxiety disorders, and showed that frequently victimized adolescents are at increased risk of multiple internalizing diagnoses.
In view of this, the next section will consider HLA genes as a general risk factor for adverse drug reactions and describe some specific HLA associations in detail.
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In contrast, it may be that in males, early separation anxiety is a more general risk factor to the genesis of severely disabling anxiety in adulthood.
Because other drugs are known to act as PXR agonists, the gene encoding PXR has potential as a more general risk factor for DILI.
While useful, these assessments are better suited to macro level analyses and may be explored in a more general risk factors study.
A combination of general risk factors and molecular diagnosis techniques may identify suitable candidates for intervention.
Moscicki[ 5] provides a comprehensive review of general risk factors, however Fairweather et al.[ 6] highlight that some variables have a better predictive capacity within certain age or gender groups.
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